Our Research Publications

Updated August 2024

Title Authors Year Journal Link to Article Intended Audience Purpose
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway Vappala S, Straus S, Pryzdial EL, Conway E, Kizhakkedathu J 2021 Blood View Researchers Basic research
Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV 2021 Transfusion View Researchers New or improved product or process
Major clinical trial finds convalescent plasma does not help patients with COVID-19 Modi D 2021 Ontario Regional Blood Coordinating Network December 2021 Newsletter View Health care providers Clinical research
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
Chapter 6: Donor selection, donor testing and pathogen reduction Drews S, Khandelwal A, Goldman M, Devine D 2021 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Estimating the impact on the inventory of implementing pathogen-reduced platelets in Canada Blake JT, McTaggart K, Couture C 2021 Transfusion View Blood operators Benchmarking and standard setting
Compliance with the massive hemorrhage protocol in trauma: a retrospective quality review Khayyat H, Callum JL, Hill-Strathy M, Strauss R, Notario L, Nathens A, da Luz L 2021 Can J Anaesth View Health care providers Clinical research
Registration errors among patients receiving blood transfusions: a national analysis from 2008 to 2017 Vijenthira S, Armali C, Downie H, Wilson A, Paton K, Berry B, Wu HX, Robitaille A, Cserti-Gazdewich C, Callum J 2021 Vox Sang View Health care providers Clinical research
Successful prenatal therapy for anti-CD36-mediated severe FNAIT by deglycosylated antibodies in a novel murine model Xu X, Chen D, Ye X, Xia W, Xu Y, Chen Y, Shao Y, Deng J, Ding H, Liu J, Wang J, Ni H, Fu Y, Santoso S 2021 Blood View Researchers Basic research
Evaluating the Tactical Combat Casualty Care principles in civilian and military settings: systematic review, knowledge gap analysis and recommendations for future research Strauss R, Menchetti I, Perrier L, Blondal E, Peng H, Sullivan-Kwantes W, Tien H, Nathens A, Beckett A, Callum J, da Luz LT 2021 Trauma Surg Acute Care Open View Health care providers Clinical research
Chapitre 15: Composants sanguins négatifs pour les anti-CMV, irradiés et lavéss Prokopchuk-Gauk O, Solh Z 2021 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM 2021 medRxiv View Researchers Clinical research
Concentré de recherche: Transfusion de plaquettes chez les enfants atteints de cancer Barty R 2021 Blood.ca website View Health care providers Benchmarking and standard setting
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O’Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
COVID-19 convalescent plasma: Interim recommendations from the AABB Cohn CS, Estcourt L, Grossman BJ, Pagano MB, Allen ES, Bloch EM, Casadevall A, Devine DV, Dunbar NM, Foroutan F, Gniadek TJ, Goel R, Gorlin J, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Beaudoin G, Tobian AAR 2021 Transfusion View Health care providers Clinical research
Evaluation of a pre-exposure prophylaxis (PrEP)/post-exposure prophylaxis (PEP) deferral policy among blood donors Saeed S, Goldman M, Uzicanin S, O'Brien SF 2021 Transfusion View Blood operators New or improved product or process
Persistence of CRISPR/Cas9 gene edited hematopoietic stem cells following transplantation: A systematic review and meta-analysis of preclinical studies Maganti HB, Bailey AJM, Kirkham AM, Shorr R, Pineault N, Allan DS 2021 Stem Cells Transl Med View Researchers Basic research
Translating bioactive peptides for COVID-19 therapy Bhullar KS, Drews SJ, Wu J 2021 Eur J Pharmacol View Researchers Basic research
Concentré de recherche: Saignement pendant la chirurgie cardiaque?: le?concentré de complexe prothrombique est-il une solution de rechange au plasma? Kron A 2021 Blood.ca website View Health care providers Clinical research
Maintaining trust in a pandemic: Blood collection agency messaging to donors and the public during the early days of COVID-19 Haw J, Thorpe R, Holloway K 2021 SocArXiv View Blood operators Ethical, legal and social implications research
COVID-19 Case Age Distribution: Correction for Differential Testing by Age Fisman DN, Greer A, Brankston G, Hillmer M, O'Brien SF, Drews S, Tuite AR 2021 Ann Intern Med View Researchers Clinical research
Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial Alshahrani MS, AlSulaibikh AH, ElTahan MR, AlFaraj SZ, Asonto LP, AlMulhim AA, AlAbbad MF, Almaghraby N, AlJumaan MA, AlJunaid TO, Darweesh MN, AlHawaj FM, Mahmoud AM, Alossaimi BK, Alotaibi SK, AlMutairi TM, AlSulaiman Pharm DD, Alfaraj D, Alhawwas R, Mbuagbaw L, Lewis K, Verhovsek M, Crowther M, Guyatt G, Alhazzani W 2021 Acad Emerg Med View Researchers Clinical research
Coagulation factor VIIa binds to herpes simplex virus 1-encoded glycoprotein C forming a factor X-enhanced tenase complex oriented on membranes Lin BH, Sutherland MR, Rosell FI, Morrissey JH, Pryzdial ELG 2020 J Thromb Haemost View Researchers Basic research
Approach to red blood cell antibody testing during pregnancy: Answers to commonly asked questions Minuk L, Clarke G, Lieberman L 2020 Can Fam Physician View Health care providers Clinical research
Fetal/neonatal alloimmune thrombocytopenia: a systematic review of impact of HLA-DRB3*01:01 on fetal/neonatal outcome Kjeldsen-Kragh J, Fergusson DA, Kjaer M, Lieberman L, Greinacher A, Murphy MF, Bussel J, Bakchoul T, Corke S, Bertrand G, Oepkes D, Baker JM, Hume H, Massey E, Kaplan C, Arnold DM, Baidya S, Ryan G, Savoia HF, Landry D, Shehata N 2020 Blood Adv View Health care providers Clinical research
L’exploration des frontières de l’hémolyse associée aux IgIV Pendergrast J, Branch D 2020 Blood.ca website View Health care providers Benchmarking and standard setting
Pre-transfusion Testing Duncan J 2020 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Stabilization of Lipid Membranes through Partitioning of the Blood Bag Plasticizer Di-2-ethylhexyl phthalate (DEHP) Bider R-C, Lluka T, Himbert S, Khondker A, Qadri SM, Sheffield WP, Rheinstädter MC 2020 Langmuir View Researchers Basic research
Vox Sanguinis International Forum on Donor Incentives: Summary Zeller MP, Ellingham D, Devine D, Lozano M, Lewis P, Zhiburt E, van der Linde L, Goldman M, Nakamura A, Inoue S, Takikawa M, Nakajima K, Turek P, Rehacek V, Sakashita AM, Kutner JM, Karim FA, Hindawi S, Jayasekara SBA, Merz EM, Gross S, Woimant G, Djoudi R, Byabazaire KD, Irving DO, Abdrakhmanova S, Khalykova A, Yilmaz S, Oruc NE, Huaynalaya IP, Ramirez LAS, Chuhriiev A 2020 Vox Sang View Blood operators Benchmarking and standard setting
An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing Wong RW, Balachandran A, Cheung PK, Cheng R, Pan Q, Stoilov P, Harrigan PR, Blencowe BJ, Branch DR, Cochrane A 2020 PLoS Pathog View Researchers Basic research
HIV residual risk in Canada under a three-month deferral for men who have sex with men O'Brien SF, Gregoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Lewin A, Seed CR 2020 Vox Sang View Researchers Other
Blood System Inventory Management Best Practices Guide Clarke G, Romans R 2020 Blood.ca website Health care providers Benchmarking and standard setting
Concentré de recherche: Estimation de la prévalence de l’hémophilie et de l’espérance de vie Iorio A 2020 Blood.ca website Health care providers Clinical research
Effects of the COVID-19 pandemic on supply and use of blood for transfusion Stanworth SJ, New HV, Apelseth TO, Brunskill S, Cardigan R, Doree C, Germain M, Goldman M, Massey E, Prati D, Shehata N, So-Osman C, Thachil J 2020 Lancet Haematol View Health care providers Clinical research
Mucosal versus systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yun YF, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras A-C 2020 medRxiv View Researchers Basic research
Thrombotic Thrombocytopenic Purpura Crowther M, Zawilska K, Mlynarski W, Arnold D 2020 McMaster Textbook of Internal Medicine Health care providers Benchmarking and standard setting
Educating the next frontier of transfusionists: a transfusion camp pilot program for nurse practitioners Shih AW, Morrison D, Sekhon AS, Lin Y, Charge S, Chipperfield K, Beaveridge J 2020 Transfusion View Health care providers Other
Influenza increases invasive meningococcal disease risk in temperate countries Salomon A, Berry I, Tuite AR, Drews S, Hatchette T, Jamieson F, Johnson C, Kwong J, Lina B, Lojo J, Mosnier A, Ng V, Vanhems P, Fisman DN 2020 Clin Microbiol Infect View Health care providers Clinical research
Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets Ni R, Neves MAD, Wu C, Cerroni SE, Flick MJ, Ni H, Weitz JI, Gross PL, Kim PY 2020 Thromb Haemost View Researchers Basic research
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM 2020 Haemophilia View Researchers Clinical research
COVID-19 versus HIT hypercoagulability Warkentin TE, Kaatz S 2020 Thromb Res View Health care providers Clinical research
Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP Khan R, Menard M, Jen C-C, Chen X, Norris PAA, Lazarus AH 2020 Blood View Researchers Basic research
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC 2020 Sci Immunol View Researchers Clinical research
Risk-assessment models for VTE and bleeding in hospitalized medical patients: an overview of systematic reviews Darzi AJ, Repp AB, Spencer FA, Morsi RZ, Charide R, Etxeandia-Ikobaltzeta I, Bauer KA, Burnett AE, Cushman M, Dentali F, Kahn SR, Rezende SM, Zakai NA, Agarwal A, Karam SG, Lotfi T, Wiercioch W, Waziry R, Iorio A, Akl EA, Schünemann HJ 2020 Blood Adv View Health care providers Clinical research
Coenzyme Q10 attenuates platelet integrin alpha II beta 3 signaling and platelet hyper-reactivity in ApoE-deficient mice Ya F, Xu XR, Tian Z, Gallant RC, Song F, Shi Y, Wu Y, Wan J, Zhao Y, Adili R, Ling W, Ni H, Yang Y 2020 Food Funct View Researchers Basic research
Fc?RI and FC?RIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/III autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2020 Haematologica View Researchers Basic research
Assessment of extracellular vesicles using IFC for application in transfusion medicine Mykhailova O, Seghatchian J, Acker JP 2020 Transfus Apher Sci View Researchers Basic research
Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities Al-Riyami AZ, Schäfer R, van den Berg K, Bloch EM, Estcourt LJ, Goel R, Hindawi S, Josephson CD, Land K, McQuilten ZK, Spitalnik SL, Wood EM, Devine DV, So-Osman C 2020 Vox Sang View Researchers Clinical research
Development and Evaluation of a Whiteboard Video Series to Support the Education and Recruitment of Committed Unrelated Donors for Hematopoietic Stem Cell Transplantation Li EW, Lee A, Vaseghi-Shanjani M, Anagnostopoulos A, Jagelaviciute G, Kum E, Petraszko T, Elmoazzen H, Allan D, Fingrut W 2020 Biol Blood Marrow Transplant View Health care providers New or improved product or process
The law and problematic marketing by private umbilical cord blood banks Murdoch B, Marcon AR, Caulfield T 2020 BMC Med Ethics View Other Ethical, legal and social implications research