Our Research Publications
Updated August 2025
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Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
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Surveillance Report 2022 | O'Brien S | 2023 | Blood.ca website | View Surveillance Report 2022 | Blood operators | Benchmarking and standard setting |
La maladie hémolytique du nouveau-né (immunisation antirhésus et anticorps non ABO) | International Collaboration for Transfusion Medicine Guidelines | 2023 | ICTMG.org | View La maladie hémolytique du nouveau-né (immunisation antirhésus et anticorps non ABO) | General public | Other |
Barriers and enablers to and strategies for pro-moting plasma donation: overarching protocol for three systematic reviews | Etherington C, Palumbo A, Holloway K, Meyer S, Labrecque M, Rubini K, Shorr R, Welch V, Gibson E, Foster T, Haw J, Vesnaver E, Maharshi MT, O'Brien S, MacPherson P, Dogba J, Steed T, Goldman M, Presseau J | 2023 | PsyArXiv | View Barriers and enablers to and strategies for pro-moting plasma donation: overarching protocol for three systematic reviews | Researchers | MSM research |
Significant rosettes observed in monocyte monolayer assay due to complement-binding antibodies | Sandhu G, Lipman T, Bodnar M, Bienz MN, Branch DR | 2023 | Transfusion | View Significant rosettes observed in monocyte monolayer assay due to complement-binding antibodies | Researchers | Basic research |
Cardiovascular events among recipients of hematopoietic stem cell transplantation-A systematic review and meta-analysis | Aghel N, Lui M, Wang V, Khalaf D, Mian H, Hillis C, Walker I, Leber B, Lipton JH, Aljama M, Lepic K, Berg T, Garcia-Horton A, Petropoulos J, Masoom H, Leong DP | 2023 | Bone Marrow Transplant | View Cardiovascular events among recipients of hematopoietic stem cell transplantation-A systematic review and meta-analysis | Researchers | Clinical research |
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα | Shen C, Mackeigan DT, Shoara AA, Xu R, Bhoria P, Karakas D, Ma W, Cerenzia E, Chen Z, Hoard B, Lin L, Lei X, Zhu G, Chen P, Johnson PE, Ni H | 2023 | J Thromb Haemost | View Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα | Researchers | Basic research |
The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023 | Murphy TJ, Swail H, Jain J, Anderson M, Awadalla P, Behl L, Brown PE, Charlton CL, Colwill K, Drews SJ, Gingras A-C, Hinshaw D, Jha P, Kanji JN, Kirsh VA, Lang ALS, Langlois M-A, Lee S, Lewin A, O’Brien SF, Pambrun C, Skead K, Stephens DA, Stein DR, Tipples G, Caeseele PGV, Evans TG, Oxlade O, Mazer BD, Buckeridge DL | 2023 | CMAJ | View The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023 | Researchers | Clinical research |
Management of Pregnancies Alloimmunized with Non-Rh and Non-K Alloantibodies | Jackson ME, Grabowska K, Lieberman L, Clarke G, Yan MTS, Canadian Obstetric Pediatric Transfusion Network | 2023 | J Obstet Gynaecol Can | View Management of Pregnancies Alloimmunized with Non-Rh and Non-K Alloantibodies | Health care providers | Clinical research |
Cost-effectiveness of Fibrinogen Concentrate vs Cryoprecipitate for Treating Acquired Hypofibrinogenemia in Bleeding Adult Cardiac Surgical Patients | Abrahamyan L, Tomlinson G, Callum J, Carcone S, Grewal D, Bartoszko J, Krahn M, Karkouti K | 2023 | JAMA Surg | View Cost-effectiveness of Fibrinogen Concentrate vs Cryoprecipitate for Treating Acquired Hypofibrinogenemia in Bleeding Adult Cardiac Surgical Patients | Health care providers | Clinical research |
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP | 2023 | Sci Rep | View Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Researchers | Basic research |
Supplemental information Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Kassardjian A, Sun E, Sookhoo J, Muthuraman K, Boligan KF, Kucharska I, Rujas E, Jetha A, Branch DR, Babiuk S, Barber B, Julien J-P | 2023 | Cell Rep | View Supplemental information Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Researchers | Basic research |
Exploring the increasing need for plasma collection: Perspectives of voluntary nonremunerated donors on payment for plasma in Canada | Holloway K | 2023 | Transfus Med | View Exploring the increasing need for plasma collection: Perspectives of voluntary nonremunerated donors on payment for plasma in Canada | Blood operators | Ethical, legal & social implications research |
Evolving the gay, bisexual and other men who have sex with men time-based deferral to sexual risk screening for all donors: The contribution of Canadian research programmes | Caffrey N, O'Brien SF, Walsh GM, Haw J, Goldman M | 2023 | Vox Sang | View Evolving the gay, bisexual and other men who have sex with men time-based deferral to sexual risk screening for all donors: The contribution of Canadian research programmes | Researchers | MSM epidemiology research |
Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Kirkham AM, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS | 2023 | Cytotherapy | View Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Researchers | Clinical research |
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Mahamad S, Li N, Arnold DM | 2023 | J Thromb Haemost | View Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Researchers | Clinical research |
White paper on pandemic preparedness in the blood supply | Strengers P, O'Brien SF, Politis C, Mayr W, Seifried E, Spencer BR | 2023 | Vox Sang | View White paper on pandemic preparedness in the blood supply | Blood operators | Benchmarking and standard setting |
TEMRA: the CD8 subset in chronic ITP? | Lazarus AH, Semple JW | 2023 | Blood | View TEMRA: the CD8 subset in chronic ITP? | Researchers | Basic research |
Rapport de surveillance | O'Brien S | 2023 | Blood.ca website | View Rapport de surveillance | Blood operators | Benchmarking and standard setting |
Doença hemolítica do recém-nascido (DHRN): doença por Rhesus (Rh) e outros anticorpos não-ABO | International Collaboration for Transfusion Medicine Guidelines | 2023 | ICTMG.org | View Doença hemolítica do recém-nascido (DHRN): doença por Rhesus (Rh) e outros anticorpos não-ABO | General public | Other |
Multinational comparison study of aircraft pilot healthcare avoidance behaviour | Hoffman WR, Patel PK, Aden J, Willis A, Acker JP, Bjerke E, Miranda E, Luster J, Tvaryanas A | 2023 | Occup Med (Lond) | View Multinational comparison study of aircraft pilot healthcare avoidance behaviour | Researchers | Clinical research |
Navigating imperfect policies to donate plasma: Survey on plasma donation and a pilot plasma donation program among men who have sex with men in Canada | Vesnaver E, Gibson E, Goldman M, Butler-Foster T, Hill NE, Lapierre D, MacDonagh R, Rubini KA, Miguel G, Rosser A, MacPherson P, Palumbo A, Randall T, Osbourne-Sorrell W, O'Brien SF, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J | 2023 | Transfusion | View Navigating imperfect policies to donate plasma: Survey on plasma donation and a pilot plasma donation program among men who have sex with men in Canada | Researchers | MSM research |
Cultured CD71+ erythroid cells modulate the host immune response | Alshalani A, Beuger BM, van Bruggen R, Acker JP, Juffermans NP | 2023 | Transfus Med | View Cultured CD71+ erythroid cells modulate the host immune response | Researchers | Basic research |
Importance du fer chez les donneurs de sang total : la perspective canadienne | Khandelwal A, Pambrun C, Goldman M | 2023 | Blood.ca website | View Importance du fer chez les donneurs de sang total : la perspective canadienne | Health care providers | Benchmarking and standard setting |
The Effect of the COVID-19 Pandemic on Unrelated Allogeneic Hematopoietic Donor Collections and Safety | Parmar G, Allan DS, Morris G, Dibdin N, Ganz K, Mostert K, Paulson K, Petraszko T, Stevens N, Seftel MD | 2023 | Curr Oncol | View The Effect of the COVID-19 Pandemic on Unrelated Allogeneic Hematopoietic Donor Collections and Safety | Health care providers | Clinical research |
Engineered Compounds to Control Ice Nucleation and Recrystallization | William N, Mangan S, Ben RN, Acker JP | 2023 | Ann Rev Biomed Eng | View Engineered Compounds to Control Ice Nucleation and Recrystallization | Researchers | New or improved product or process |
The under-appreciated world of the serpin family of serine proteinase inhibitors | Bouton M-C, Geiger M, Sheffield WP, Irving JA, Lomas DA, Song S, Satyanarayanan RS, Zhang L, McFadden G, Lucas AR | 2023 | EMBO Mol Med | View The under-appreciated world of the serpin family of serine proteinase inhibitors | Researchers | Basic research |
Diminished Neutralization Capacity of SARS-CoV-2 Omicron BA.1 in Donor Plasma Collected from January to March 2021 | Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ | 2023 | Microbiol Spectr | View Diminished Neutralization Capacity of SARS-CoV-2 Omicron BA.1 in Donor Plasma Collected from January to March 2021 | Researchers | Clinical research |
Risk of variant Creutzfeldt–Jakob disease in a simulated cohort of Canadian blood donors | Pozzo di Borgo A, Germain M, O'Brien SF, Delage G, Renaud C, Lewin A | 2023 | Vox Sang | View Risk of variant Creutzfeldt–Jakob disease in a simulated cohort of Canadian blood donors | Researchers | Clinical research |
Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Leong DP, Zhang A, Breznik JA, Clare R, Huynh A, Mushtaha M, Rangarajan S, Stacey H, Kim PY, Loeb M, Denburg JA, Mertz D, Chagla Z, Nazy I, Miller MS, Bowdish DME, Duong M | 2023 | PLoS One | View Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Researchers | Clinical research |
FAQ : Information destinée aux professionnels de la santé qui commandent des concentrés de granulocytes | Stepien J, Robert M-H | 2023 | Blood.ca website | View FAQ : Information destinée aux professionnels de la santé qui commandent des concentrés de granulocytes | Health care providers | Benchmarking and standard setting |
SARS-CoV-2 cross-sectional seroprevalence study among public school staff in Metro Vancouver after the first Omicron wave in British Columbia, Canada | Watts AW, Mâsse LC, Goldfarb DM, Irvine MA, Hutchison SM, Muttucomaroe L, Poon B, Barakauskas VE, O’Reilly C, Bosman E, Reicherz F, Coombs D, Pitblado M, O’Brien SF, Lavoie PM | 2023 | BMJ Open | View SARS-CoV-2 cross-sectional seroprevalence study among public school staff in Metro Vancouver after the first Omicron wave in British Columbia, Canada | Researchers | Clinical research |
The Specialist in Transfusion Science program | Clarke G, Holovati J | 2023 | Immunohematology | View The Specialist in Transfusion Science program | Researchers | Benchmarking and standard setting |
Plan de mejora para el proceso de inventarios de la empresa Zoomania clinica Veterinaria S.A.S | Ramirez-Arcos S | 2023 | Tecnológico de Antioquia | View Plan de mejora para el proceso de inventarios de la empresa Zoomania clinica Veterinaria S.A.S | Researchers | Basic research |
Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness | Shaver N, Katz M, Darko Asamoah G, Linkins L-A, Abdelkader W, Beck A, Bennett A, Hughes SE, Smith M, Begin M, Coyle D, Piggott T, Kagina BM, Welch V, Colijn C, Earn DJD, El Emam K, Heffernan J, O'Brien SF, Wilson K, Collins E, Navarro T, Beyene J, Boutron I, Bowdish D, Cooper C, Costa A, Curran J, Griffith L, Hsu A, Grimshaw J, Langlois M-A, Li X, Pham-Huy A, Raina P, Rubini M, Thabane L, Wang H, Xu L, Brouwers M, Horsley T, Lavis J, Iorio A, Little J | 2023 | Vaccine | View Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness | Researchers | Benchmarking and standard setting |
Do Children With an Allergic Transfusion Reaction Require Premedication or All Blood Products? | Bahabri A, Barty R, Li N, Liu Y, Kovalova T, Chan AKC | 2023 | J Pediatr Hematol Oncol | View Do Children With an Allergic Transfusion Reaction Require Premedication or All Blood Products? | Health care providers | Clinical research |
How do we forecast tomorrow's transfusion? Applying social science approaches to meet tomorrow's transfusion needs: Blood donors and donation | Haw J, Holloway K, Goldman M | 2023 | Transfus Clin Biol | View How do we forecast tomorrow's transfusion? Applying social science approaches to meet tomorrow's transfusion needs: Blood donors and donation | Researchers | Ethical, legal & social implications research |
Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model | Wabnitz H, Cruz-Leal Y, Lazarus AH | 2023 | Transfusion | View Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model | Researchers | Basic research |
La maladie hémolytique du nouveau-né (incompatibilité ABO) | International Collaboration for Transfusion Medicine Guidelines | 2023 | ICTMG.org | View La maladie hémolytique du nouveau-né (incompatibilité ABO) | General public | Other |
Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression | Li J, Karakas D, Xue F, Chen Y, Zhu G, Yucel YH, MacParland SA, Zhang H, Semple JW, Freedman J, Shi Q, Ni H | 2023 | Research | View Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression | Researchers | Basic research |
Transfusion Camp Rwanda: A prospective feasibility study evaluating the delivery of Transfusion Camp to a multidisciplinary group of postgraduate medical trainees in Rwanda | Hagumimana J, Skelton T, Pendergrast J, Nizeyimana F, Masaisa F, Kanyamuhunga A, Gashaija C, Chargé S, Kapitany C, Morgan M, Meirovich H, Lin Y | 2023 | Transfusion | View Transfusion Camp Rwanda: A prospective feasibility study evaluating the delivery of Transfusion Camp to a multidisciplinary group of postgraduate medical trainees in Rwanda | Health care providers | Education research |
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Gabe C, Liu Y, Duncan J, St John M, Lucier KJ, Kimmel D, Kelton JG, Arnold DM | 2023 | Platelets | View Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Researchers | Clinical research |
An expanded role for blood donor emerging pathogens surveillance | O’Brien SF, Goldman M, Drews S | 2023 | CMAJ | View An expanded role for blood donor emerging pathogens surveillance | Blood operators | New or improved product or process |
Transmission of Variant Creutzfeldt-Jakob Disease Through Blood Transfusion and Plasma-Derived Products: A Narrative Review of Observed and Modeled Risks | Pozzo di Borgo A, Rochette S, Gaussen A, O'Brien SF, Germain M, Renaud C, Lewin A | 2023 | Transfus Med Rev | View Transmission of Variant Creutzfeldt-Jakob Disease Through Blood Transfusion and Plasma-Derived Products: A Narrative Review of Observed and Modeled Risks | Researchers | Benchmarking and standard setting |
Taking lessons from nature to improve cell therapy cryopreservation | Acker J, William N, Coatham M | 2023 | Cell Gene Ther Insights | View Taking lessons from nature to improve cell therapy cryopreservation | Researchers | Basic research |
Molecular Screening of Blood Donors for Babesia in Tyrol, Austria | Bloch EM, Siller A, Tonnetti L, Drews SJ, Spencer BR, Hedges D, Mergenthal T, Weber-Schehl M, Astl M, Patel EU, Gaber M, Schennach H | 2023 | Transfus Med Hemother | View Molecular Screening of Blood Donors for Babesia in Tyrol, Austria | Researchers | Clinical research |
Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S | Huynh A, Arnold DM, Michael JV, Clare R, Smith JW, Daka M, Ianosi-Irimie M, McKenzie SE, Kelton JG, Nazy I | 2023 | Blood Adv | View Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S | Researchers | Clinical research |
Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates | Li W, William N, Acker JP | 2023 | Transfusion | View Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates | Researchers | Basic research |
The high prevalence of occult hepatitis B infections among the partners of chronically infected HBV blood donors emphasizes the potential residual risk to blood safety | Ye X, Li T, Yu B, Zeng J, Shi Y, Xie H, Branch DR, Loriamini M, Li B, Chen L | 2023 | J Med Virol | View The high prevalence of occult hepatitis B infections among the partners of chronically infected HBV blood donors emphasizes the potential residual risk to blood safety | Blood operators | Clinical research |
HIV Pre-Exposure Prophylaxis, Blood Donor Deferral, Occult Infection, and Risk of HIV Transmission by Transfusion: A Fine Balance Between Evidence-Based Donor Selection Criteria and Transfusion Safety | Leblanc J-F, Custer B, Van de Laar T, Drews SJ, Germain M, Lewin A | 2023 | Transfus Med Rev | View HIV Pre-Exposure Prophylaxis, Blood Donor Deferral, Occult Infection, and Risk of HIV Transmission by Transfusion: A Fine Balance Between Evidence-Based Donor Selection Criteria and Transfusion Safety | Researchers | Clinical research |
Hepatitis B virus genotype surveillance in Canadian blood donors and a referred patient population, 2016–2021 | Osiowy C, Giles E, Lowe CF, Matic N, Murphy DG, Uzicanin S, Drews SJ, O'Brien SF | 2023 | Vox Sang | View Hepatitis B virus genotype surveillance in Canadian blood donors and a referred patient population, 2016–2021 | Researchers | Epidemiology research |