Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
The cellular pathophysiology of immune thrombocytopenia Semple JW 2013 ISBT Sci Ser View Researchers Basic research
Thermal reversal of polyvalent choline phosphate, a multivalent universal biomembrane adhesive Yu X, Zou Y, Horte S, Janzen J, Kizhakkedathu JN, Brooks DE 2013 Biomacromolecules View Researchers Basic research
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C 2012 Toxins (Basel) View Researchers Basic research
ResearchUnit: One in a million: Modelling rare blood flow Blake J, Clarke G 2019 Blood.ca website View Researchers Clinical research
Effect of liposome treatment on hemorheology and metabolic profile of human red blood cells during hypothermic storage Da Silveira Cavalcante L, Acker J, Holovati J 2018 Biopreserv Biobank View Researchers Basic research
Reducing red blood cell folate testing: a case study in utilisation management Ismail O, Chin-Yee I, Gob A, Bhayana V, Rutledge A 2019 BMJ Open Quality View Researchers Basic research
Pathophysiology of immune thrombocytopenia Li J, Sullivan JA, Ni H 2018 Curr Opin Hematol View Researchers Other
Concentré de recherche : Plasma : c'est dans la poche Sheffield W, Jenkins C 2018 Blood.ca website View Researchers Basic research
An enzymatic pathway in the human gut microbiome that converts A to universal O type blood Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG 2019 Nat Microbiol View Researchers Basic research
Is Platelet Desialylation a Novel Biomarker and Therapeutic Target in Immune Thrombocytopenia? Li J, Sullivan J, Ni H 2020 Cell Immunol View Researchers Basic research
Population pharmacokinetics of two recombinant human coagulation factor preparations in patients with hemophilia A Hua BL, Chelle P, Yeung C, Gu J, Zhao YQ, Iorio A 2019 Zhonghua Xue Ye Xue Za Zhi View Researchers Clinical research
Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells Jahan S, Kaushal R, Pasha R, Pineault N 2021 Transfus Med Rev View Researchers New or improved product or process
Is the COVID-19 thrombotic catastrophe complement-connected? Conway EM, Pryzdial ELG 2020 J Thromb Haemost View Researchers Basic research
Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly Niu C, Yang Y, Huynh A, Nazy I, Kaltashov IA 2020 Biophys J View Researchers Basic research
SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system Srivastava K, Albasri J, Alsuhaibani OM, Aljasem HA, Bueno MU, Antonacci T, Branch DR, Denomme GA, Flegel WA 2021 Transfusion View Researchers Basic research
Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fc? receptor inhibition Norris PAA, Kaur G, Khan R, Zhu G, Ni H, Lazarus AH 2021 Blood View Researchers Basic research
An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors Drews SJ, Bodnar M, Gill B, Carson D, Hawes G, Yi QL, Tran V, Zhou HY, Bigham M, O'Brien SF 2022 Transfusion View Researchers Benchmarking and standard setting
Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety Blumenstein I, Shanbhag S, Langguth P, Kalra PA, Zoller H, Lim W 2021 Expert Opin Drug Saf View Researchers Basic research
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Robbins NF, Orjuela G, Jenkins C, Conrod V, Yi Q-L, O’Brien SF, Drews SJ 2022 Microbiol Spectr View Researchers Benchmarking and standard setting
Blood is a politic of place-making: Blackness, queerness and the construction of the donor Dryden OH 2022 Harriet’s Legacies: Race, Historical Memory, and Futures in Canada View Researchers MSM research
Automated closed volume reduction process for apheresis stem cell grafts: From development to clinical implementation Howell A, Letcher B, Murphy K, Elmoazzen H, Petraszko T, Acker JP, Pineault N, Holovati JL 2022 Transfusion View Researchers New or improved product or process
A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma Li N, Zeller MP, Shih AW, Heddle NM, St. John M, Bégin P, Callum J, Arnold DM, Akbari-Moghaddam M, Down DG, Jamula E, Devine DV, Tinmouth A 2022 Transfusion View Researchers Clinical research
Current status of rapid bacterial detection methods for platelet components: A 20-year review by the ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria Schmidt M, Ramirez-Arcos S, Stiller L, McDonald C, ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria 2022 Vox Sang View Researchers Benchmarking and standard setting
Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia Guo L, Yang L, Speck ER, Aslam R, Kim M, McKenzie CGJ, Lazarus AH, Ni H, Hou M, Freedman J, Semple JW 2014 Blood View Researchers Basic research
Antibody-mediated immune suppression is improved when blends of anti-RBC monoclonal antibodies are used in mice Bernardo L, Amash A, Marjoram D, Lazarus AH 2016 Blood View Researchers Basic research
Blood groups and susceptibility to virus infection: new developments Branch DR 2010 Curr Opin Hematol View Researchers Basic research
Concentré de recherche: Amélioration des résultats pour les patients présentant des troubles auto-immuns de la fonction plaquettaire Arnold D 2017 Blood.ca website View Researchers Basic research
Dengue virus replication by platelets Pryzdial ELG, Sutherland MR, Simon AY 2017 ISBT Sci Ser View Researchers Basic research
DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis Amatullah H, Shan Y, Beauchamp BL, Gali PL, Gupta S, Maron-Gutierrez T, Speck ER, Fox-Robichaud AE, Tsang JLY, Mei SHJ, Mak TW, Rocco PRM, Semple JW, Zhang H, Hu P, Marshall JC, Stewart DJ, Harper M-E, Liaw PC, Liles WC, dos Santos CC, Canadian Critical Care Translational Biology Group (CCCTBG) 2017 Am J Respir Crit Care Med View Researchers Basic research
Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC, Provost P 2015 Platelets View Researchers Basic research
FcgRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Nazi I, Arnold DM, Smith JW, Horsewood P, Moore JC, Warkentin TE, Crowther MA, Kelton JG 2013 J Thromb Haemost View Researchers Basic research
gT-S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo Sheffield WP, Lambourne MD, Eltringham-Smith LJ, Bhakta V, Arnold DM, Crowther MA 2014 J Thromb Haemost View Researchers Basic research
Identification of potential protein quality markers in pathogen inactivated and gamma-irradiated red cell concentrates Chen D, Schubert P, Devine DV 2017 Proteomics Clin Appl View Researchers Basic research
Microfluidic determination of lymphocyte vascular deformability: effects of intracellular complexity and early immune activation Kang N, Guo Q, Islamzada E, Ma H, Scott MD 2018 Integr Biol View Researchers Basic research
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice Chen J, Reheman A, Gushiken FC, Nolasco L, Fu X, Moake JL, Ni H, Lopez JA 2011 J Clin Invest View Researchers Basic research
Oxford's Systematic Review Initiative: leading by example in evidence-based transfusion medicine Fergusson DA 2016 Transfus Med View Researchers Clinical research
Polymer-mediated immunocamouflage of red blood cells: effects of polymer size on antigenic and immunogenic recognition of allogeneic donor blood cells Wang D, Kyluik DL, Murad KL, Toyofuku WM, Scott MD 2011 Sci China Life Sci View Researchers Basic research
Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate Lambourne MD, Eltringham-Smith LJ, Gataiance S, Arnold DM, Crowther MA, Sheffield WP 2012 J Thromb Haemost View Researchers Basic research
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy Deng X, Duffy SP, Myrand-Lapierre M-E, Matthews K, Santoso AT, Du Y-L, Ryan KS, Ma H 2015 Malar J View Researchers New or improved product or process
RhoA/ROCK signaling contributes to sex differences in the activation of human platelets Schubert P, Coupland D, Nombalais M, Walsh G, Devine DV 2016 Thromb Res View Researchers Basic research
Shining a light on AHG "blind" spot(s) Branch DR, Westhoff CM 2016 Transfusion View Researchers Basic research
The effects of rejuvenation during hypothermic storage on red blood cell membrane remodeling Kurach JDR, Almizraq R, Bicalho B, Acker JP, Holovati JL 2014 Transfusion View Researchers Basic research
The potential utility of methoxypoly(ethylene glycol)-mediated prevention of rhesus blood group antigen RhD recognition in transfusion medicine Wang D, Toyofuku WM, Scott MD 2012 Biomaterials View Researchers Basic research
Two-year follow-up of donors in a large national study of ferritin testing Goldman M, Uzicanin S, Osmond L, Yi Q-L, Scalia V, O'Brien SF 2018 Transfusion View Researchers Clinical research
Protocol for a phase III, non-inferiority, randomised comparison of a new fibrinogen concentrate versus cryoprecipitate for treating acquired hypofibrinogenaemia in bleeding cardiac surgical patients: the FIBRES trial Karkouti K, Callum J, Rao V, Heddle N, Farkouh ME, Crowther MA, Scales DC 2018 BMJ Open View Researchers Clinical research
Patient Blood Management: Recommendations From the 2018 Frankfurt Consensus Conference Mueller MM, Van Remoortel H, Meybohm P, Aranko K, Aubron C, Burger R, Carson JL, Cichutek K, De Buck E, Devine D, Fergusson D, Folléa G, French C, Frey KP, Gammon R, Levy JH, Murphy MF, Ozier Y, Pavenski K, So-Osman C, Tiberghien P, Volmink J, Waters JH, Wood EM, Seifried E, ICC PBM Frankfurt Group 2019 JAMA View Researchers Clinical research
Concentré de recherche: Combattre l'inflammation par l'inflammation Lazarus A 2019 Blood.ca website View Researchers Clinical research
Comparative seasonalities of influenza A, B and 'common cold' coronaviruses - setting the scene for SARS-CoV-2 infections and possible unexpected host immune interactions Liu Y, Lam TTY, Lai FYL, Krajden M, Drews SJ, Hatchette TF, Fraaij PLA, van Kampen JJA, Badarch D, Nymadawa P, Tee KK, Lee HK, Koay ESC, Jennings L, Koopmans M, Tang JW 2020 J Infect View Researchers Clinical research
Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A Solms A, Shah A, Berntorp E, Tiede A, Iorio A, Linardi C, Ahsman M, Mancuso ME, Zhivkov T, Lissitchkov T 2020 Ann Hematol View Researchers Clinical research
A prospective observational study of the incidence, natural history, and risk factors for intravenous immunoglobulin-mediated hemolysis Pendergrast J, Armali C, Callum J, Cserti-Gazdewich C, Jiwajee A, Lieberman L, Lau W, Lin Y, Parmar N, Pavenski K, Riden LS, Shehata N, Willie-Ramharack K, Tomlinson G, Tong TN, Binnington B, Branch DR 2021 Transfusion View Researchers Clinical research