Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination Breznik JA, Huynh A, Zhang A, Bilaver L, Bhakta H, Stacey HD, Ang JC, Bramson JL, Nazy I, Miller MS, Denburg J, Costa AP, Bowdish DME 2022 J Immunol View Health care providers Clinical research
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH 2022 PLoS One View Researchers Basic research
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM 2022 Blood View Researchers Basic research
Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP 2022 Transfusion View Researchers New or improved product or process
Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia Kaur MN, Arnold DM, Heddle NM, Cook RJ, Hsia C, Blostein M, Jamula E, Sholzberg M, Lin Y, Kassis J, Larratt L, Tinmouth A, Carruthers J, Li N, Liu Y, Xie F 2022 Blood Adv View Health care providers Clinical research
Loss of repeat convalescent plasma donors due to waning anti-SARS-CoV-2 plaque reduction neutralization test titers (April-December 2020) Drews S, Devine D, McManus J, Mendoza E, Manguiat K, Girardin R, Dupuis A, McDonough K, Lin J, Evans D, Pambrun C, Drebot M, Wood H 2022 Transfus Med Rev View Blood operators New or improved product or process
Plaquettes extraites de la couche leucoplaquettaire à teneur réduite en agents pathogènes Blais-Normandin I, Tordon B, Anani W 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Methods to Evaluate the Potential Clinical Significance of Antibodies to Red Blood Cells Boligan KF, Sandhu G, Branch DR 2022 Curr Protoc View Researchers Benchmarking and standard setting
Management of immune‐mediated thrombocytopenia Gabe C, Arnold D, Smith J, T W 2022 Rossi's Principles of Transfusion Medicine View Health care providers Benchmarking and standard setting
Why We Swab: A library of stories in stem cell donation Jagelaviciute G, Kum E, Li EW, Rosenfeld A, Williams K, Kandel R, DeGurse N, Park B, Okonofua S, Sano L, Gerofsky M, Sharp A, Hatkar R, Thyagu S, Fingrut WB 2022 Transfusion View Health care providers Ethical, legal & social implications research
Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 Viruses Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ 2022 Microbiol Spectr View Health care providers Benchmarking and standard setting
Les fournisseurs de sang canadiens : un rôle croissant dans la surveillance de la santé publique? O’Brien SF, Drews SJ, Lewin A, Osiowy C, Drebot MA, Renaud C 2022 Relevé des maladies transmissibles au Canada View Health care providers New or improved product or process
Circulaire d'information utilisation de composants sanguins humains: Plaquettes Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N 2022 Transfusion View Researchers Clinical research
HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men Aubé E, Lewin A, O'Brien SF, Grégoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Seed CR, Camirand Lemyre F, the Surveillance RA, Policy Subgroup of the ISBT Transfusion Transmitted Infectious Diseases Working Party 2022 Vox Sang View Blood operators MSM research
The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B 2022 J Infect Dis View Researchers Clinical research
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA 2022 Transfusion View Researchers MSM research
Chapter 5. Concentrates for hemostatic disorders and hereditary angioedema Poon MC, Goodyear D, Rydz N, Lee A 2022 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Benchmarking and standard setting
A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies Yao Z, Drecun L, Aboualizadeh F, Kim SJ, Li Z, Wood H, Valcourt EJ, Manguiat K, Plenderleith S, Yip L, Li X, Zhong Z, Yue FY, Closas T, Snider J, Tomic J, Drews SJ, Drebot MA, McGeer A, Ostrowski M, Mubareka S, Rini JM, Owen S, Stagljar I 2021 Nat Commun View Researchers New or improved product or process
Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation Schubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV 2021 Transfusion View Researchers Basic research
Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial Writing Committee for the REMAP-CAP Investigators 2021 JAMA View Health care providers Clinical research
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time Stonebraker JS, O'Mahony B, Noone D, Iorio A 2021 Haemophilia View Researchers Benchmarking and standard setting
Blood shortages planning in Canada: The National Emergency Blood Management Committee experience during the first 6 months of the COVID-19 pandemic Prokopchuk-Gauk O, Petraszko T, Nahirniak S, Doncaster C, Levy I 2021 Transfusion View Regulators Benchmarking and standard setting
Concentré de recherche: Précision et efficacité accrues dans la gestion des réserves de sang Li N 2021 Blood.ca website View Health care providers New or improved product or process
Examining prescribing practices with respect to oral iron supplementation for post-partum anemia: a retrospective review Iancu AM, Buckstein J, Melamed N, Lin Y 2021 J Matern Fetal Neonatal Med View Health care providers Clinical research
Evaluation of the sexual health in people living with hemophilia Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A 2021 Haemophilia View Researchers Clinical research
Circulaire d'information utilisation de composants sanguins humains: Composants plasmatiques Jenkins C 2021 Blood.ca website Health care providers Benchmarking and standard setting
Chapter 4: Clinical transfusion procedures Clarke G, Al-Riyami AZ, Roxby D 2021 Educational Modules on Clinical Use of Blood View Health care providers Benchmarking and standard setting
ResearchUnit: Platelet Transfusion in Children with Cancer Barty R 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM 2021 Transfusion View Researchers Clinical research
Irradiated, Washed and CMV Seronegative Blood Components Prokopchuk-Gauk O, Solh Z 2021 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF 2021 Transfusion View Researchers Clinical research
Managing drug shortages during a pandemic: tocilizumab and COVID-19 Verma AA, Pai M, Saha S, Bean S, Fralick M, Gibson JL, Greenberg RA, Kwan JL, Lapointe-Shaw L, Tang T, Morris AM, Razak F 2021 CMAJ View Health care providers Benchmarking and standard setting
Surveillance report 2020 O'Brien S 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Répercussions de la COVID-19 sur le don de sang au Canada Khandelwal A 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Syndrome respiratoire aigu post-transfusionnel (TRALI) Gupta A, Yan M 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Adjunct Immune Globulin for Vaccine-Induced Immune Thrombotic Thrombocytopenia Bourguignon A, Arnold DM, Warkentin TE, Smith JW, Pannu T, Shrum JM, Al Maqrashi ZAA, Shroff A, Lessard M-C, Blais N, Kelton JG, Nazy I 2021 N Engl J Med View Health care providers Clinical research
ResearchUnit: Treatment and detection of vaccine-induced thrombotic thrombocytopenia (VITT) Abe T 2021 Blood.ca website View Health care providers Clinical research
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H 2021 Transfusion View Researchers New or improved product or process
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M 2021 Transfusion View Researchers Basic research
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME 2021 J Trauma Acute Care Surg View Researchers Benchmarking and standard setting
ResearchUnit: Treating bleeding during cardiac surgery: Is prothrombin complex concentrate a substitute for plasma? Kron A 2021 Blood.ca website View Health care providers Clinical research
The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation Halpenny M, William N, Elmoazzen H, Giulivi A, Martin L, Perron D, Bredeson C, Hamelin L, Huebsch L, Yang L, Birch P, Acker JP 2021 Cytotherapy View Blood operators New or improved product or process
Treatment-induced cerebral sinus venous thrombosis in childhood acute lymphoblastic malignancies: New risk factors to consider El-Khoury H, Saifi O, Haddad S, Chahrour M, Ghanem KM, Mubarak Y, Tamim H, Makki M, Zakka C, Chan AK, Mahfouz R, Tarek N, El-Solh H, Abboud MR, Saab R, Muwakkit SA 2021 Pediatr Blood Cancer View Health care providers Clinical research
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals Bulmer T, Volders D, Blake J, Kamal N 2021 Front Neurol View Researchers New or improved product or process
Extensive variability in platelet, bleeding, and QOL outcome measures in adult and pediatric ITP: Communication from the ISTH SSC subcommittee on platelet immunology Al-Samkari H, Cronin A, Arnold DM, Rodeghiero F, Grace RF 2021 J Thromb Haemost View Health care providers Benchmarking and standard setting
A prospective multi-faceted interventional study of blood bank technologist screening of red blood cell transfusion orders: The START study Kron AT, Collins A, Cserti-Gazdewich C, Pendergrast J, Webert K, Lieberman L, Zeller MP, Harding SR, Nahirniak S, Prokopchuk-Gauk O, Lin Y, Mendez B, Armali C, Lee C, Watson D, Arnott D, Xun F, Blain H, Panchuk H, Hughes H, Chorneyko K, Angers M, Pilutti N, Lett R, Dowsley S, Ruijs T, Cupido T, Kichinko T, Thompson T, Afshar-Ghotli Z, Callum J, University of Toronto Quality in Utilization, Education and Safety in Transfusion (QUEST) Research Program 2021 Transfusion View Health care providers Clinical research
Tantalum-containing meso-porous glass fibres for hemostatic applications Nagrath M, Rahimnejad Yazdi A, Rafferty A, Daly D, Rahman SU, Gallant RC, Ni H, Arany PR, Towler MR 2021 Mater Today Commun View Researchers Basic research