Our Research Publications

Updated August 2024

Title Authors Year Journal Link to Article Intended Audience Purpose
Pathogen Inactivation Technologies: The Advent of Pathogen-Reduced Blood Components to Reduce Blood Safety Risk Devine DV, Schubert P 2016 Hematol Oncol Clin North Am View Blood operators Other
Small molecule phagocytosis inhibitors for immune cytopenias Neschadim A, Kotra LP, Branch DR 2016 Autoimmun Rev View Researchers Basic research
Development of standard definitions for surveillance of complications related to blood donation Goldman M, Land K, Robillard P, Wiersum-Osselton J 2016 Vox Sang View Blood operators Benchmarking and standard setting
Laboratory management of perinatal patients with apparently "new" anti-D Hannon J, Clarke G 2016 Immunohematology View Researchers Basic research
Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside Crow AR, Lazarus AH 2016 Semin Hematol View Researchers Basic research
Molecular immunohematology at Canadian Blood Services: red cell antigen genotyping Goldman M, Hannaford K, Hannon J, Berardi P 2016 Blood.ca website View Health care providers Other
O-aryl-glycoside ice recrystallization inhibitors as novel cryoprotectants: A structure-function study Capicciotti CJ, Mancini RS, Turner TR, Koyama T, Alteen MG, Doshi M, Inada T, Acker JP, Ben RN 2016 ACS Omega View Researchers Basic research
Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study Tay J, Allan D, Beattie S, Bredeson C, Fergusson D, Maze D, Sabloff M, Thavorn K, Tinmouth A 2016 BMJ Open View Researchers Clinical research
Routine nucleic acid testing of blood donations fails to detect all human immunodeficiency virus–positive blood donors Fearon M, Scalia V, Lane D, Bigham M, Hawes G, O'Brien S, Kadkhoda K 2016 Transfusion View Health care providers Clinical research
Value of MMA crossmatch? Tong TN, Cserti-Gazdewich CM, Branch DR 2016 Transfus Med View Researchers Basic research
A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial Ypma PF, van der Meer PF, Heddle NM, van Hilten JA, Stijnen T, Middelburg RA, Hervig T, van der Bom JG, Brand A, Kerkhoffs JL 2016 BMJ Open View Researchers Clinical research
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L 2016 eLife View Researchers Clinical research
Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis Cameron-Vendrig A, Reheman A, Siraj MA, Xu XR, Wang Y, Lei X, Afroze T, Shikatani E, El-Mounayri O, Noyan H, Weissleder R, Ni H, Husain M 2016 Diabetes View Researchers Basic research
Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock McIntyre L, Rowe BH, Walsh TS, Gray A, Arabi Y, Perner A, Gordon A, Marshall J, Cook D, Fox-Robichaud A, Bagshaw SM, Green R, Schweitzer I, Turgeon A, Zarychanski R, English S, Chassé M, Stiell I, Fergusson D 2016 BMJ Open View Health care providers Clinical research
Outbreak of acute hepatitis B virus infection associated with exposure to acupuncture Rempel S, Murti M, Buxton J, Stephens W, Watterson M, Andonov A, Fung C, Ramler G, Bigham M, Lem M 2016 Canada Communicable Disease Report View Health care providers Clinical research
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
Acetylsalicyclic acid for the prevention and treatment of thromboembolic diseases Webert K, Kelton J 2016 Aspirin and related drugs View Health care providers Clinical research
Applications of Liposomes in Biopreservation Da Silveira Cavalcante L, Holovati J, Acker J 2016 Multiscale technologies for cryomedicine: implementation from nano to macroscale View Researchers Basic research
Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial Atkins HL, Bowman M, Allan D, Anstee G, Arnold DL, Bar-Or A, Bence-Bruckler I, Birch P, Bredeson C, Chen J, Fergusson D, Halpenny M, Hamelin L, Huebsch L, Hutton B, Laneuville P, Lapierre Y, Lee H, Martin L, McDiarmid S, O'Connor P, Ramsay T, Sabloff M, Walker L, Freedman MS 2016 Lancet View Researchers Clinical research
Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells Briard JG, Jahan S, Chandran P, Allan D, Pineault N, Ben RN 2016 ACS Omega View Researchers Basic research
Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization Stowell SR 2016 Blood View Researchers Basic research
How do I interpret a confidence interval? O'Brien SF, Yi QL 2016 Transfusion View Researchers Other
Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial Eikelboom JW, Cook RJ, Barty R, Liu Y, Arnold DM, Crowther MA, Devereaux PJ, Ellis M, Figueroa P, Gallus A, Hirsh J, Kurz A, Roxby D, Sessler DI, Sharon Y, Sobieraj-Teague M, Warkentin TE, Webert KE, Heddle NM 2016 Transfus Med Rev View Researchers Clinical research
ResearchUnit: Data mining 2: digging for deeper understanding of donors and transfusion outcome Fergusson DA, Acker J 2016 Blood.ca website View Other Other
The M358R variant of α1-proteinase inhibitor inhibits coagulation factor VIIa Sheffield WP, Bhakta V 2016 Biochem Biophys Res Commun View Researchers Basic research
Alleviation of gram-negative bacterial lung inflammation by targeting HECTD2 Kapur R, Semple JW 2016 Ann Transl Med View Researchers Basic research
Dengue virus persists and replicates during storage of platelet and red blood cell units Sutherland MR, Simon AY, Serrano K, Schubert P, Acker JP, Pryzdial ELG 2016 Transfusion View Researchers Basic research
Effects of methoxypoly (Ethylene glycol) mediated immunocamouflage on leukocyte surface marker detection, cell conjugation, activation and alloproliferation Kyluik-Price DL, Scott MD 2016 Biomaterials View Researchers Basic research
Evaluating the "family veto" of consent for organ donation Toews M, Caulfield T 2016 CMAJ View Health care providers Other
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE 2016 Biomaterials View Researchers Basic research
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK 2016 Blood View Researchers Clinical research
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang View Researchers Basic research
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood View Researchers Clinical research
Using simulation for strategic blood supply chain design in the Canadian prairies Blake J, McTaggart K 2016 Proceedings of the 6th International Conference on SIMULTECH View Blood operators New or improved product or process
ResearchUnit: Data mining: digging for deeper understanding of blood components and transfusion outcomes Heddle NM, Acker JP 2016 Blood.ca website View Other Other
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier Singh S, Dubinsky-Davidchik IS, Kluger R 2016 Org Biomol Chem View Researchers Basic research
Antibody-mediated immune suppression is improved when blends of anti-RBC monoclonal antibodies are used in mice Bernardo L, Amash A, Marjoram D, Lazarus AH 2016 Blood View Researchers Basic research
Introducing the red cell storage lesion Chen D, Serrano K, Devine DV 2016 ISBT Sci Ser View Blood operators Basic research
Myasthenia gravis treated with autologous hematopoietic stem cell transplantation Bryant A, Atkins H, Pringle C, Allan D, Anstee G, Bence-Bruckler I, Hamelin L, Hodgins M, Hopkins HS, Huebsch L, McDiarmid S, Sabloff M, Sheppard D, Tay J, Bredeson C 2016 JAMA Neurol View Researchers Clinical research
Plasma and cryoprecipitate for transfusion Stanworth SJ, Tinmouth AT 2016 Rossi's Principles of Transfusion Medicine View Researchers Basic research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
BK virus prophylaxis with levofloxacin--reply Gill JS, Knoll GA, Humar A 2015 JAMA View Other Other
Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor-recipient continuum Chasse M, McIntyre L, Tinmouth A, Acker J, English SW, Knoll G, Forster A, Shehata N, Wilson K, van Walraven C, Ducharme R, Fergusson DA 2015 BMJ Open View Researchers Other
Determining the Volume of Additive Solution and Residual Plasma in Whole Blood Filtered and Buffy Coat Processed Red Cell Concentrates Jordan A, Acker J 2015 Transfus Med Hemother View Researchers New or improved product or process
Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannee C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Levesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E 2015 PNAS View Researchers Basic research
Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis Shehata N, Forster AJ, Lawrence N, Ducharme R, Fergusson DA, Chassé M, Rothwell DM, Hébert PC, Tinmouth AT, Wilson K 2015 PLoS One View Health care providers Clinical research
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J 2015 J Cell Mol Med View Researchers Basic research
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A 2015 Haemophilia View Health care providers Clinical research
Alloimmune Red Blood Cell Antibodies: Prevalence and Pathogenicity in a Canadian Prenatal Population Zwingerman R, Jain V, Hannon J, Zwingerman N, Clarke G 2015 J Obstet Gynaecol Can View Health care providers Clinical research
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai Z-m, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H 2015 Nat Commun View Researchers Basic research