Our Research Publications
Updated August 2025
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Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
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Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics | Yang X, Kang N, Toyofuku WM, Scott MD | 2018 | Immunobiology | View Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics | Researchers | Basic research |
Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Jenkins C | 2018 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Health care providers | Benchmarking and standard setting |
Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls | Mannucci PM, Nobili A, Marchesini E, Oliovecchio E, Cortesi L, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Peyvandi F, Iorio A | 2018 | Haemophilia | View Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls | Health care providers | Clinical research |
Risk of exposure to Zika virus and impact on cord blood banking and adult unrelated donors in hematopoietic cell transplantation: the Canadian Blood Services experience | Adams Z, Morris G, Campbell T, Mostert K, Dibdin N, Fearon M, Elmoazzen H, Mercer D, Young K, Allan D | 2018 | Biol Blood Marrow Transplant | View Risk of exposure to Zika virus and impact on cord blood banking and adult unrelated donors in hematopoietic cell transplantation: the Canadian Blood Services experience | Blood operators | Clinical research |
Devices to Reduce the Volume of Blood Taken for Laboratory Testing in ICU Patients: A Systematic Review | Siegal DM, Manning N, Jackson Chornenki NL, Hillis CM, Heddle NM | 2018 | J Intensive Care Med | View Devices to Reduce the Volume of Blood Taken for Laboratory Testing in ICU Patients: A Systematic Review | Researchers | New or improved product or process |
Splenectomy for immune thrombocytopenia: down but not out | Chaturvedi S, Arnold DM, McCrae KR | 2018 | Blood | View Splenectomy for immune thrombocytopenia: down but not out | Health care providers | Clinical research |
Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents | Xu XR, Yousef GM, Ni H | 2018 | Blood | View Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents | Health care providers | Clinical research |
Concentré de recherche : Une façon nouvelle d'évaluer la qualité des globules rouges | Acker J | 2018 | Blood.ca website | View Concentré de recherche : Une façon nouvelle d'évaluer la qualité des globules rouges | Researchers | Clinical research |
Differential diagnoses for sepsis?induced disseminated intravascular coagulation: communication from the SSC of the ISTH | Iba T, Levy J, Wada H, Thachil J, E. Warkentin T, Levi M, Subcommittee on Disseminated Intravascular Coagulation | 2018 | J Thromb Haemost | View Differential diagnoses for sepsis?induced disseminated intravascular coagulation: communication from the SSC of the ISTH | Other | Benchmarking and standard setting |
Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT | Krauel K, Preuße P, Warkentin TE, Trabhardt C, Brandt S, Jensch I, Mandelkow M, Hammer E, Hammerschmidt S, Greinacher A | 2018 | Blood | View Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT | Researchers | Basic research |
Surveillance Report 2017 | O'Brien S | 2018 | Blood.ca website | View Surveillance Report 2017 | Other | Other |
Blood coagulation dissected | Pryzdial ELG, Lee FMH, Lin BH, Carter RLR, Tegegn TZ, Belletrutti MJ | 2018 | Transfus Apher Sci | View Blood coagulation dissected | Health care providers | Other |
Anti-RhD reduces levels of detectable RhD antigen following anti-RhD infusion | Sullivan HC, Arthur CM, Thompson L, Patel SR, Stowell SR, Hendrickson JE, Lazarus AH | 2018 | Transfusion | View Anti-RhD reduces levels of detectable RhD antigen following anti-RhD infusion | Health care providers | Clinical research |
Circular of information for the use of human blood components: Plasma components | Jenkins C | 2018 | Blood.ca website | View Circular of information for the use of human blood components: Plasma components | Health care providers | Benchmarking and standard setting |
Fetal and neonatal alloimmune thrombocytopenia: Novel mechanisms of miscarriage learned from placental pathology in animal models | Yougbare I, Zdravic D, Ni H | 2018 | J Pediatr Pediatr Med | View Fetal and neonatal alloimmune thrombocytopenia: Novel mechanisms of miscarriage learned from placental pathology in animal models | Researchers | Basic research |
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water | Devine DV | 2018 | JAMA Oncol | View Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water | Health care providers | New or improved product or process |
Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain | Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AG, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT | 2018 | Am J Physiol Regul Integr Comp Physiol | View Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain | Researchers | Basic research |
Red cell supernatant effects on endothelial cell function and innate immune activation is influenced by donor age and sex | Kipkeu BJ, Almizraq R, Branch DR, Acker JP, Holovati JL | 2018 | ISBT Sci Ser | View Red cell supernatant effects on endothelial cell function and innate immune activation is influenced by donor age and sex | Researchers | Basic research |
ResearchUnit: Platelet protein GPIba plays an important role in regulating platelet-mediated production of thrombopoietin by the liver | Ni H | 2018 | Blood.ca website | View ResearchUnit: Platelet protein GPIba plays an important role in regulating platelet-mediated production of thrombopoietin by the liver | Other | Other |
Troubles de l'hémostase et angioedéme héréditaire | Poon MC, Goodyear MD, Rydz N, Lee A | 2018 | Guide de la pratique transfusionnelle | View Troubles de l'hémostase et angioedéme héréditaire | Health care providers | Other |
Window to the Unknown: Using Storytelling to Identify Learning Needs for the Intrinsic Competencies Within an Online Needs Assessment | Tseng EK, Jo D, Shih AW, De Wit K, Chan TM | 2018 | AEM Educ Train | View Window to the Unknown: Using Storytelling to Identify Learning Needs for the Intrinsic Competencies Within an Online Needs Assessment | Researchers | Education research |
The Massive Online Needs Assessment (MONA) to inform the development of an emergency haematology educational blog series | Chan TM, Jo D, Shih AW, Bhagirath VC, Castellucci LA, Yeh C, Thoma B, Tseng EK, de Wit K | 2018 | Perspect Med Educ | View The Massive Online Needs Assessment (MONA) to inform the development of an emergency haematology educational blog series | Health care providers | Education research |
Effect of liposome treatment on hemorheology and metabolic profile of human red blood cells during hypothermic storage | Da Silveira Cavalcante L, Acker J, Holovati J | 2018 | Biopreserv Biobank | View Effect of liposome treatment on hemorheology and metabolic profile of human red blood cells during hypothermic storage | Researchers | Basic research |
Pathophysiology of immune thrombocytopenia | Li J, Sullivan JA, Ni H | 2018 | Curr Opin Hematol | View Pathophysiology of immune thrombocytopenia | Researchers | Other |
Importance du fer chez les donneurs de sang total : la perspective canadienne | Pambrun C, Goldman M | 2018 | Blood.ca website | View Importance du fer chez les donneurs de sang total : la perspective canadienne | Health care providers | Other |
Concentré de recherche : Plasma : c'est dans la poche | Sheffield W, Jenkins C | 2018 | Blood.ca website | View Concentré de recherche : Plasma : c'est dans la poche | Researchers | Basic research |
Neutropenia and monocytopenia in recurrent anaphylactoid reactions after red blood cell transfusions in a woman with immunoglobulin A (IgA) deficiency and anti-IgA | Warkentin TE, Morin P-A, Heddle NM | 2018 | Transfusion | View Neutropenia and monocytopenia in recurrent anaphylactoid reactions after red blood cell transfusions in a woman with immunoglobulin A (IgA) deficiency and anti-IgA | Health care providers | Clinical research |
An international investigation into AB plasma administration in hospitals: how many AB plasma units were infused? The HABSWIN study | Zeller MP, Barty R, Dunbar NM, Elahie A, Flanagan P, Garritsen H, Kutner JM, Pagano MB, Poglod R, Rogers TS, Staves J, van Wordragen-Vlaswinkel M, Zwaginga JJ, Murphy MF, Heddle NM, Yazer MH | 2018 | Transfusion | View An international investigation into AB plasma administration in hospitals: how many AB plasma units were infused? The HABSWIN study | Health care providers | Clinical research |
Label-free assessment of red blood cell storage lesions by deep learning | Doan M, Sebastian JA, Pinto PN, McQuin C, Goodman A, Wolkenhauer O, Parsons MJ, Acker JP, Rees P, Hennig H, Kolios MC, Carpenter AE | 2018 | bioRxiv | View Label-free assessment of red blood cell storage lesions by deep learning | Researchers | New or improved product or process |
Transfusion-associated circulatory overload prevention: a retrospective observational study of diuretic use | Lin Y, Cohen R, Armali C, Callum J, Cserti-Gazdewich C, Lieberman L, Pendergrast J | 2018 | Vox Sang | View Transfusion-associated circulatory overload prevention: a retrospective observational study of diuretic use | Researchers | Clinical research |
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. | Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA | 2018 | Blood Adv | View Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. | Researchers | Basic research |
Albumin | Clarke G, Yan M | 2018 | Clinical Guide to Transfusion | View Albumin | Health care providers | Other |
McMaster RARE-Best practices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome | Legault K, Schunemann H, Hillis C, Yeung C, Akl EA, Carrier M, Cervera R, Crowther M, Dentali F, Erkan D, Espinosa G, Khamashta M, Meerpohl JJ, Moffat K, O'Brien S, Pengo V, Rand JH, Rodriguez Pinto I, Thom L, Iorio A | 2018 | J Thromb Haemost | View McMaster RARE-Best practices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome | Health care providers | Benchmarking and standard setting |
Designing the blood supply chain: how much, how and where? | Osorio AF, Brailsford SC, Smith HK, Blake J | 2018 | Vox Sang | View Designing the blood supply chain: how much, how and where? | Other | New or improved product or process |
Timing of gamma irradiation and blood donor sex influences in vitro characteristics of red blood cells | de Korte D, Thibault L, Handke W, Harm SK, Morrison A, Fitzpatrick A, Marks DC, Yi QL, Acker JP | 2018 | Transfusion | View Timing of gamma irradiation and blood donor sex influences in vitro characteristics of red blood cells | Blood operators | New or improved product or process |
Two-year follow-up of donors in a large national study of ferritin testing | Goldman M, Uzicanin S, Osmond L, Yi Q-L, Scalia V, O'Brien SF | 2018 | Transfusion | View Two-year follow-up of donors in a large national study of ferritin testing | Researchers | Clinical research |
Protocol for a phase III, non-inferiority, randomised comparison of a new fibrinogen concentrate versus cryoprecipitate for treating acquired hypofibrinogenaemia in bleeding cardiac surgical patients: the FIBRES trial | Karkouti K, Callum J, Rao V, Heddle N, Farkouh ME, Crowther MA, Scales DC | 2018 | BMJ Open | View Protocol for a phase III, non-inferiority, randomised comparison of a new fibrinogen concentrate versus cryoprecipitate for treating acquired hypofibrinogenaemia in bleeding cardiac surgical patients: the FIBRES trial | Researchers | Clinical research |
Investigations for fetal and neonatal alloimmune thrombocytopenia: communication from the SSC of the ISTH | Petermann R, Bakchoul T, Curtis BR, Mullier F, Miyata S, Arnold DM, Subcommittee on platelet immunology | 2018 | J Thromb Haemost | View Investigations for fetal and neonatal alloimmune thrombocytopenia: communication from the SSC of the ISTH | Health care providers | Benchmarking and standard setting |
Transfusion de plaquettes, l'allo-immunisation et la prise en charge de l'état réfractaire aux plaquettes | Zeller M, Petraszko T | 2018 | Guide de la pratique transfusionnelle | View Transfusion de plaquettes, l'allo-immunisation et la prise en charge de l'état réfractaire aux plaquettes | Health care providers | Other |
Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort | Feldman BM, Rivard GE, Babyn P, Wu JKM, Steele M, Poon M-C, Card RT, Israels SJ, Laferriere N, Gill K, Chan AK, Carcao M, Klaassen RJ, Cloutier S, Price VE, Dover S, Blanchette VS | 2018 | Lancet Haematol | View Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort | Health care providers | Clinical research |
Circulaire d'information utilisation de composants sanguins humains: Composants plasmatiques | Jenkins C | 2018 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Composants plasmatiques | Health care providers | Benchmarking and standard setting |
The effect of unmeasurable endogenous plasma factor activity levels on factor VIII dosing in patients with severe hemophilia A | McEneny-King A, Chelle P, Iorio A, Edginton AN | 2018 | Thromb Res | View The effect of unmeasurable endogenous plasma factor activity levels on factor VIII dosing in patients with severe hemophilia A | Health care providers | Clinical research |
A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting | Sirianni G, Perri G, Callum J, Gardner S, Berall A, Selby D | 2018 | Am J Hosp Palliat Care | View A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting | Researchers | Clinical research |
ResearchUnit: Improving the usefulness of a laboratory tool to match donors and patients | Acker J, Branch D | 2018 | Blood.ca website | View ResearchUnit: Improving the usefulness of a laboratory tool to match donors and patients | Other | Other |
Chloride and other electrolyte concentrations in commonly available 5% albumin products | Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B, on behalf of The Canadian Critical Care Trials Group | 2018 | Crit Care Med | View Chloride and other electrolyte concentrations in commonly available 5% albumin products | Health care providers | Clinical research |
Rapport de surveillance 2017 | O'Brien S | 2018 | Blood.ca website | View Rapport de surveillance 2017 | Other | Other |
Red blood cells, still vital after all these years: Commentary on Canadian Blood Services' International Symposium 2017 | Qadri SM, Donkor DA, Yan M, Ning S, Branch DR, Seghatchian J, Sheffield WP | 2018 | Transfus Apher Sci | View Red blood cells, still vital after all these years: Commentary on Canadian Blood Services' International Symposium 2017 | Researchers | Other |
Megakaryocyte apoptosis in immune thrombocytopenia | Vrbensky JR, Nazy I, Toltl LJ, Ross C, Ivetic N, Smith JW, Kelton JG, Arnold DM | 2018 | Platelets | View Megakaryocyte apoptosis in immune thrombocytopenia | Researchers | Basic research |
ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis | Branch DR, Hellberg Å, Bruggeman CW, Storry JR, Sakac D, Blacquiere M, Tong TN, Burke-Murphy E, Binnington B, Parmar N, Riden LS, Willie K, Armali C, Aziz J, Lieberman L, Laroche V, Callum J, Lin Y, Shehata N, Pavenski K, Lau W, Hannach B, Kuijpers TW, Olsson ML, Cserti-Gazdewich C, Pendergrast J | 2018 | Blood | View ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis | Health care providers | Clinical research |
Concentré de recherche: Un modèle de changement : prédiction de l'impact d'améliorations à l'échelle du système | Blake J | 2018 | Blood.ca website | View Concentré de recherche: Un modèle de changement : prédiction de l'impact d'améliorations à l'échelle du système | Researchers | Basic research |